Effect of cAMP on TGFβ1-Induced Corneal Keratocyte-Myofibroblast Transformation
نویسندگان
چکیده
منابع مشابه
Effect of cAMP on TGFbeta1-induced corneal keratocyte-myofibroblast transformation.
PURPOSE TGFbeta is the major mediator to induce myofibroblast differentiation in the corneal wound-healing process. Elevated cAMP can reduce TGFbeta-induced fibrosis in other tissues. This study was conducted to determine whether elevated cAMP can inhibit TGFbeta1-induced rabbit corneal keratocyte-myofibroblast transformation. METHODS Primary isolated rabbit corneal keratocytes were cultured ...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2009
ISSN: 1552-5783
DOI: 10.1167/iovs.08-2444